Potions Library

Slay the Spire 2 Potions

Search the current potion database, filter by class or colorless options, and keep tactical effect text visible while you compare short-term combat tools.
Last verified: March 7, 2026Indexed potions: 63

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Search and filter the current Slay the Spire 2 potion database

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Showing 63 of 63 potions in All.

Ashwater potions icon in Slay the Spire 2

Ashwater

Uncommon

Ironclad

Exhaust any number of cards in your Hand.
Attack Potion potions icon in Slay the Spire 2

Attack Potion

Common

Colorless

Choose 1 of 3 random Attack cards to add into your Hand. It's free to play this turn.
Beetle Juice potions icon in Slay the Spire 2

Beetle Juice

Rare

Colorless

Enemy's attacks deal 30% less damage for the next 4 turns.
Blessing of the Forge potions icon in Slay the Spire 2

Blessing of the Forge

Uncommon

Colorless

Upgrade all cards in your Hand for the rest of combat.
Block Potion potions icon in Slay the Spire 2

Block Potion

Common

Colorless

Gain 12 Block.
Blood Potion potions icon in Slay the Spire 2

Blood Potion

Common

Ironclad

Heal for 20% of your Max HP.
Bone Brew potions icon in Slay the Spire 2

Bone Brew

Uncommon

Necrobinder

Summon 15.
Bottled Potential potions icon in Slay the Spire 2

Bottled Potential

Rare

Colorless

Shuffle ALL your cards into your Draw Pile. Draw 5 cards.
Clarity Extract potions icon in Slay the Spire 2

Clarity Extract

Uncommon

Colorless

Draw 1 card. At the start of your next 3 turns, draw 1 additional card.
Colorless Potion potions icon in Slay the Spire 2

Colorless Potion

Common

Colorless

Choose 1 of 3 random Colorless cards to add into your Hand. It's free to play this turn.
Cosmic Concoction potions icon in Slay the Spire 2

Cosmic Concoction

Rare

Regent

Add 3 Upgraded Colorless cards into your Hand.
Cunning Potion potions icon in Slay the Spire 2

Cunning Potion

Uncommon

Silent

Add 3 Upgraded Shivs into your Hand.
Cure All potions icon in Slay the Spire 2

Cure All

Uncommon

Colorless

Gain Colorless Energy. Draw 2 cards.
Dexterity Potion potions icon in Slay the Spire 2

Dexterity Potion

Common

Colorless

Gain 2 Dexterity.
Distilled Chaos potions icon in Slay the Spire 2

Distilled Chaos

Rare

Colorless

Play the top 3 cards of your Draw Pile.
Droplet of Precognition potions icon in Slay the Spire 2

Droplet of Precognition

Rare

Colorless

Choose a card in your Draw Pile and add it into your Hand.
Duplicator potions icon in Slay the Spire 2

Duplicator

Uncommon

Colorless

This turn, your next card is played an extra time.
Energy Potion potions icon in Slay the Spire 2

Energy Potion

Common

Colorless

Gain Colorless EnergyColorless Energy.
Entropic Brew potions icon in Slay the Spire 2

Entropic Brew

Rare

Colorless

Fill all your empty potion slots with random potions.
Essence of Darkness potions icon in Slay the Spire 2

Essence of Darkness

Rare

Defect

Channel a Dark for each of your Orb Slots.
Explosive Ampoule potions icon in Slay the Spire 2

Explosive Ampoule

Common

Colorless

Deal 10 damage to ALL enemies.
Fairy in a Bottle potions icon in Slay the Spire 2

Fairy in a Bottle

Rare

Colorless

When you would die, instead this potion is discarded and you heal to 30% of your Max HP.
Fire Potion potions icon in Slay the Spire 2

Fire Potion

Common

Colorless

Deal 20 damage.
Flex Potion potions icon in Slay the Spire 2

Flex Potion

Common

Colorless

Gain 5 Strength. At the end of your turn, lose 5 Strength.
Focus Potion potions icon in Slay the Spire 2

Focus Potion

Common

Defect

Gain 2 Focus.
Fortifier potions icon in Slay the Spire 2

Fortifier

Uncommon

Colorless

Triple your Block.
Foul Potion potions icon in Slay the Spire 2

Foul Potion

Event

Colorless

Deal 12 damage to EVERYONE. Can be thrown at the Merchant for 100 Gold instead.
Fruit Juice potions icon in Slay the Spire 2

Fruit Juice

Rare

Colorless

Gain 5 Max HP.
Fysh Oil potions icon in Slay the Spire 2

Fysh Oil

Uncommon

Colorless

Gain 1 Strength and 1 Dexterity.
Gambler's Brew potions icon in Slay the Spire 2

Gambler's Brew

Uncommon

Colorless

Discard any number of cards, then draw that many.
Ghost in a Jar potions icon in Slay the Spire 2

Ghost in a Jar

Rare

Silent

Gain 1 Intangible.
Gigantification Potion potions icon in Slay the Spire 2

Gigantification Potion

Rare

Colorless

The next Attack you play deals triple damage.
Glowwater Potion potions icon in Slay the Spire 2

Glowwater Potion

Event

Colorless

Exhaust your Hand. Draw 10 cards.
Heart of Iron potions icon in Slay the Spire 2

Heart of Iron

Uncommon

Colorless

Gain 7 Plating.
King's Courage potions icon in Slay the Spire 2

King's Courage

Uncommon

Regent

Forge 15.
Liquid Bronze potions icon in Slay the Spire 2

Liquid Bronze

Uncommon

Colorless

Gain 3 Thorns.
Liquid Memories potions icon in Slay the Spire 2

Liquid Memories

Rare

Colorless

Put a card from your Discard Pile into your Hand. It costs 0 Colorless Energy this turn.
Lucky Tonic potions icon in Slay the Spire 2

Lucky Tonic

Rare

Colorless

Gain 1 Buffer.
Mazaleth's Gift potions icon in Slay the Spire 2

Mazaleth's Gift

Rare

Colorless

Gain 1 Ritual.
Orobic Acid potions icon in Slay the Spire 2

Orobic Acid

Rare

Colorless

Add a random Attack, Skill, and Power into your Hand. They're free to play this turn.
Poison Potion potions icon in Slay the Spire 2

Poison Potion

Common

Silent

Apply 6 Poison.
Pot of Ghouls potions icon in Slay the Spire 2

Pot of Ghouls

Rare

Necrobinder

Add 2 Souls into your Hand.
Potion of Binding potions icon in Slay the Spire 2

Potion of Binding

Uncommon

Colorless

Apply 1 Weak and 1 Vulnerable to ALL enemies.
Potion of Capacity potions icon in Slay the Spire 2

Potion of Capacity

Uncommon

Defect

Gain 2 Orb Slots.
Potion of Doom potions icon in Slay the Spire 2

Potion of Doom

Common

Necrobinder

Apply 33 Doom.
Potion-Shaped Rock potions icon in Slay the Spire 2

Potion-Shaped Rock

Token

Colorless

Deal 15 damage.
Powdered Demise potions icon in Slay the Spire 2

Powdered Demise

Uncommon

Colorless

Enemy loses 9 HP at the end of each of its turns.
Power Potion potions icon in Slay the Spire 2

Power Potion

Common

Colorless

Choose 1 of 3 random Power cards to add into your Hand. It's free to play this turn.
Radiant Tincture potions icon in Slay the Spire 2

Radiant Tincture

Uncommon

Colorless

Gain Colorless Energy. Gain an additional Colorless Energy at the start of your next 3 turns.
Regen Potion potions icon in Slay the Spire 2

Regen Potion

Uncommon

Colorless

Gain 5 Regen.
Shackling Potion potions icon in Slay the Spire 2

Shackling Potion

Rare

Colorless

ALL enemies lose 7 Strength this turn.
Ship in a Bottle potions icon in Slay the Spire 2

Ship in a Bottle

Rare

Colorless

Gain 10 Block. Next turn, gain 10 Block.
Skill Potion potions icon in Slay the Spire 2

Skill Potion

Common

Colorless

Choose 1 of 3 random Skill cards to add into your Hand. It's free to play this turn.
Snecko Oil potions icon in Slay the Spire 2

Snecko Oil

Rare

Colorless

Draw 7 cards. Randomize the cost of cards in your Hand this turn.
Soldier's Stew potions icon in Slay the Spire 2

Soldier's Stew

Rare

Ironclad

All cards containing Strike gain 1 Replay this combat.
Speed Potion potions icon in Slay the Spire 2

Speed Potion

Common

Colorless

Gain 5 Dexterity. At the end of your turn, lose 5 Dexterity.
Stable Serum potions icon in Slay the Spire 2

Stable Serum

Uncommon

Colorless

Retain your Hand for 2 turns.
Star Potion potions icon in Slay the Spire 2

Star Potion

Common

Regent

Gain Regent Star EnergyRegent Star EnergyRegent Star Energy.
Strength Potion potions icon in Slay the Spire 2

Strength Potion

Common

Colorless

Gain 2 Strength.
Swift Potion potions icon in Slay the Spire 2

Swift Potion

Common

Colorless

Draw 3 cards.
Touch of Insanity potions icon in Slay the Spire 2

Touch of Insanity

Uncommon

Colorless

Choose a card in your Hand. It is free to play this combat.
Vulnerable Potion potions icon in Slay the Spire 2

Vulnerable Potion

Common

Colorless

Apply 3 Vulnerable.
Weak Potion potions icon in Slay the Spire 2

Weak Potion

Common

Colorless

Apply 3 Weak.

Potions FAQ

Does this page include all current Slay the Spire 2 potions?

This database shows the locally verified potion coverage for the current build and does not claim more than the site has actually indexed.

Can I filter potions by class?

Yes. The toolbar lets you switch between class-specific and colorless potion groups without leaving the page.

What should I read after the potion database?

Most players should jump next to cards, relics, or early-pick guides so the tactical value of a potion lines up with the rest of the run.